Description

Artemether is a potent, semi-synthetic derivative of artemisinin, a naturally occurring sesquiterpene lactone endoperoxide. This compound is a cornerstone in modern antimalarial therapy, valued for its rapid action against Plasmodium falciparum, including chloroquine-resistant strains. It is an essential active pharmaceutical ingredient (API) primarily required by pharmaceutical manufacturers for the production of artemisinin-based combination therapies (ACTs), which are the first-line treatment recommended by the WHO for uncomplicated malaria.

Application

• Pharmaceutical API: Primary use as the active ingredient in antimalarial combination drugs, most notably in co-formulations with Lumefantrine.
• Antimalarial Formulations: Manufacture of oral solid dosage forms (tablets, capsules) and injectable solutions for the treatment of acute malaria infections.
• Veterinary Medicine: Potential application in veterinary pharmaceuticals for the treatment of parasitic infections in animals.
• Research & Development: Used as a reference standard in analytical laboratories and for pharmacological research into novel antiparasitic agents.
• Global Health Programs: Sourced by procurement agencies and NGOs for large-scale public health initiatives in malaria-endemic regions.

Basic Information

Product Name	Artemether
CAS No.	71963-77-4
Molecular Formula	C16H26O5
Molecular Weight	298.37 g/mol
Synonyms	Dihydroartemisinin Methyl Ether; Artemotil; β-Arteether; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin; Arteether; SM-224; RP-54476; (+)-Artemether
EINECS	Contact for details

Quality Control

Our Artemether is manufactured under strict quality management systems. It is typically supplied to meet Pharmaceutical Grade standards, with specifications aligned with major pharmacopoeias such as USP, EP, and CP. Each batch undergoes comprehensive analytical testing including assay, identification, and impurity profiling via HPLC. Certificates of Analysis (COA) are provided to ensure full traceability and compliance with your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Specific Optical Rotation	+168° to +173°
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.