Description

α-Propoxycarbonyldihydroartemisine is a key semi-synthetic derivative of artemisinin, a sesquiterpene lactone with a peroxide bridge. This compound is valued for its role as a crucial synthetic intermediate in the development of novel antimalarial agents and other bioactive molecules. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of advanced therapeutic compounds.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of next-generation artemisinin-based antimalarial drugs and combination therapies (ACTs).
• Medicinal Chemistry Research: Used in the discovery and development of new therapeutic agents targeting parasitic and other infectious diseases.
• Fine Chemical Synthesis: Serves as a specialized precursor for creating complex molecules with potential biological activity in academic and industrial research.
• Reference Standard: Employed as an analytical standard in quality control laboratories for the identification and quantification of related artemisinin derivatives.

Basic Information

Product Name	α-Propoxycarbonyldihydroartemisine
CAS No.	71939-53-2
Molecular Formula	C21H32O6
Molecular Weight	380.48 g/mol
Synonyms	Artemisinin, 3-(1-carboxypropoxy)-1,2,3,4,4a,5,6,7,8,8a-decahydro-4a,8-dimethyl-2-oxo-, (3R,4aS,8aS)-; Dihydroartemisinin propyl carbonate; α-Propoxycarbonyl dihydroartemisinin; 3α-Propoxycarbonyl dihydroartemisinin; (3R,4aS,8aS)-3-(1-Carboxypropoxy)-1,2,3,4,4a,5,6,7,8,8a-decahydro-4a,8-dimethyl-2-oxonaphthalene; Artemisinin derivative 71939-53-2; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our α-Propoxycarbonyldihydroartemisine is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.