Description

4-(Chloromethyl)Pyridine-2-Carbonitrile is a versatile and high-value heterocyclic building block featuring both a reactive chloromethyl group and a nitrile functionality. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where it serves as a key precursor. It is primarily sought after by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced materials, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, particularly those containing pyridine and piperidine cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Ligand and Catalyst Development: Serves as a starting material for creating complex chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, metal-organic frameworks (MOFs), and other advanced materials.
• Chemical Biology Probes: Useful for constructing molecular probes and tags due to its ability to undergo selective reactions with biological nucleophiles.

Basic Information

Product Name	4-(Chloromethyl)Pyridine-2-Carbonitrile
CAS No.	71935-33-6
Molecular Formula	C7H5ClN2
Molecular Weight	152.58 g/mol
Synonyms	2-Cyano-4-(chloromethyl)pyridine; 4-(Chloromethyl)picolinonitrile; 4-Chloromethyl-2-cyanopyridine; 2-Pyridinecarbonitrile, 4-(chloromethyl)-; Picolinonitrile, 4-(chloromethyl)-; (2-Cyano-4-pyridyl)methyl chloride
EINECS	Contact for details

Quality Control

Our 4-(Chloromethyl)Pyridine-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.