Description

4-(Hydroxymethyl)Picolinitrile is a versatile bifunctional organic intermediate featuring both a hydroxymethyl group and a nitrile moiety on a pyridine ring. This unique structure makes it a valuable building block for synthesizing complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists for creating novel active ingredients and fine chemicals. The compound's reactivity allows for selective modifications, enabling the construction of diverse heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Used to create novel pyridine-based ligands for metal catalysis and coordination chemistry.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers and functional materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals, dyes, and other performance materials.

Basic Information

Product Name	4-(Hydroxymethyl)Picolinitrile
CAS No.	71935-32-5
Molecular Formula	C7H6N2O
Molecular Weight	134.14 g/mol
Synonyms	4-(Hydroxymethyl)-2-pyridinecarbonitrile; 2-Cyano-4-pyridinemethanol; 4-Pyridinemethanol, 2-cyano-; (2-Cyano-4-pyridinyl)methanol; Picolinonitrile, 4-(hydroxymethyl)-; 4-Hydroxymethylpicolinonitrile; 2-Pyridinecarbonitrile, 4-(hydroxymethyl)-
EINECS	Contact for details

Quality Control

Our 4-(Hydroxymethyl)Picolinitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.