Description

6-Aza-Spiro[3.5]Nonane is a high-value, nitrogen-containing spirocyclic building block of significant interest in advanced organic synthesis. Its unique rigid, three-dimensional structure makes it a critical scaffold for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily sought after by medicinal chemists and process R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Medicinal Chemistry Scaffold: Used to introduce conformational restraint and improve the pharmacokinetic properties (e.g., metabolic stability, solubility) of lead compounds.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Ligand Synthesis: Employed in the creation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to develop tool compounds and probes for studying biological pathways and target validation.
• Advanced Material Science: Acts as a monomer or cross-linker for designing polymers with specific thermal or mechanical properties.

Basic Information

Product Name	6-Aza-Spiro[3.5]Nonane
CAS No.	71873-27-3
Molecular Formula	C8H15N
Molecular Weight	125.21 g/mol
Synonyms	6-Azaspiro[3.5]nonane; 1-Azaspiro[3.5]nonane; Hexamethyleneimine, spiro-; Spiro[3.5]nonan-6-amine; Azaspiro[3.5]nonane; 6-Aza-spiro[3.5]nonane; 71873-27-3
EINECS	Contact for details

Quality Control

Every batch of 6-Aza-Spiro[3.5]Nonane is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, typically including results for identification, assay purity (by GC or HPLC), and impurity profiling.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using inert gas purging or desiccants.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.