Description

[(3R)-Tetrahydro-2,6-Dioxo-2H-Pyran-3-Yl]-Carbamic Acid Phenylmethyl is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry and functional groups make it a valuable building block for constructing complex molecules with specific biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for complex target molecules.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to introduce the (3R)-tetrahydro-2,6-dioxo-2H-pyran moiety into target compounds.
• Protease Inhibitor Research: Serves as a precursor or core structure in the synthesis of potential protease inhibitor candidates.
• Chemical Biology & Medicinal Chemistry: Used in the design and synthesis of chemical probes and libraries for biological screening and structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds at various scales.
• Academic Research: Employed in university and institutional labs for methodological development in organic chemistry and catalysis.

Basic Information

Product Name	[(3R)-Tetrahydro-2,6-Dioxo-2H-Pyran-3-Yl]-Carbamic Acid Phenylmethyl
CAS No.	71869-80-2
Molecular Formula	C13H13NO5
Molecular Weight	263.25 g/mol
Synonyms	(3R)-3-[(Benzyloxycarbonyl)amino]dihydro-2H-pyran-2,6(3H)-dione; (R)-3-((Benzyloxycarbonyl)amino)-3,4-dihydro-2H-pyran-2,6(3H)-dione; (R)-3-((Benzyloxycarbonyl)amino)dihydro-2H-pyran-2,6(3H)-dione; (R)-3-((Cbz)amino)dihydro-2H-pyran-2,6(3H)-dione; (R)-3-(Cbz-amino)dihydro-2H-pyran-2,6(3H)-dione; (R)-N-Cbz-3-aminodihydro-2H-pyran-2,6(3H)-dione; Benzyl (3R)-2,6-dioxotetrahydro-2H-pyran-3-ylcarbamate
EINECS	Contact for details

Quality Control

Our [(3R)-Tetrahydro-2,6-Dioxo-2H-Pyran-3-Yl]-Carbamic Acid Phenylmethyl is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, chiral HPLC) are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.