Description

(+)-8-Phenylmenthyl Chloroacetate CAS NO 71804-27-8 is a high-purity chiral auxiliary and derivatizing agent, crucial for achieving stereoselectivity in complex organic syntheses. Its value lies in providing exceptional diastereofacial control in asymmetric reactions, enabling the production of enantiomerically pure intermediates. This compound is essential for research chemists and process development scientists in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Asymmetric Synthesis: As a chiral auxiliary in Diels-Alder reactions, conjugate additions, and other cycloadditions to induce high enantioselectivity.
• Pharmaceutical Intermediate Manufacturing: For the stereocontrolled synthesis of key chiral building blocks used in drug discovery and development.
• Derivatization Agent: Used to prepare diastereomeric derivatives of chiral alcohols or amines for analysis or purification via chromatography.
• Catalyst and Ligand Preparation: Serving as a precursor for the synthesis of novel chiral ligands and organocatalysts.
• Academic and Industrial R&D: A critical reagent for methodological studies in organic chemistry and process optimization.
• Fine Chemical Production: Enabling the commercial-scale manufacture of specialty chemicals with defined stereochemistry.

Basic Information

Product Name	(+)-8-Phenylmenthyl Chloroacetate
CAS No.	71804-27-8
Molecular Formula	C19H27ClO2
Molecular Weight	322.87 g/mol
Synonyms	(1R,2S,5R)-8-Phenylmenthyl Chloroacetate; (+)-8-Phenylmenthyl Chloroacetate; (1R,2S,5R)-2-(2-Chloroacetyl)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-yl]benzene; 8-Phenylmenthyl Chloroacetate; (1R)-(-)-8-Phenylmenthyl Chloroacetate; Phenylmenthyl Chloroacetate; Chloroacetic Acid (1R,2S,5R)-8-Phenylmenthyl Ester
EINECS	Contact for details

Quality Control

Our (+)-8-Phenylmenthyl Chloroacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for asymmetric synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.