Description

1-(5-Chloropyridin-2-Yl)Ethanol is a versatile chloropyridine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its bifunctional structure, featuring both a reactive pyridine ring and a hydroxymethyl group, enabling its use in constructing complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the chloropyridine moiety for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Research & Development: A valuable building block for medicinal chemistry and process chemistry in both academic and industrial R&D settings.

Basic Information

Product Name	1-(5-Chloropyridin-2-Yl)Ethanol
CAS No.	71777-68-9
Molecular Formula	C7H8ClNO
Molecular Weight	157.60 g/mol
Synonyms	2-(1-Hydroxyethyl)-5-chloropyridine; 5-Chloro-2-(1-hydroxyethyl)pyridine; (5-Chloro-2-pyridinyl)ethanol; 1-(5-Chloro-2-pyridinyl)ethanol; α-Methyl-5-chloro-2-pyridinemethanol
EINECS	Contact for details

Quality Control

Our production of 1-(5-Chloropyridin-2-Yl)Ethanol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and quantify impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.