Description

Tiquizium Bromide is a quaternary ammonium compound with anticholinergic and antispasmodic properties. This active pharmaceutical ingredient (API) is valued for its targeted action on smooth muscle, making it a critical component in specialized therapeutic formulations. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of gastrointestinal and genitourinary antispasmodic medications.

Application

• Pharmaceutical API: Primary use as the active ingredient in antispasmodic and anticholinergic drug formulations.
• Gastrointestinal Therapeutics: Key component in medications designed to treat conditions like irritable bowel syndrome (IBS), gastritis, and intestinal hypermotility.
• Genitourinary Spasmolytics: Used in formulations targeting urinary incontinence, bladder spasms, and related urological disorders.
• Chemical Synthesis Intermediate: Serves as a building block or precursor in the synthesis of more complex pharmaceutical molecules.
• Pharmacological Research: Employed in preclinical and clinical studies investigating muscarinic receptor antagonists.
• Veterinary Pharmaceuticals: Potential application in veterinary medicine for treating animal gastrointestinal spasms.

Basic Information

Product Name	Tiquizium Bromide
CAS No.	71731-58-3
Molecular Formula	C₂₁H₂₈BrNO₃S
Molecular Weight	454.42 g/mol
Synonyms	TIQUIZIUM BROMIDE; 3-(Di-2-thienylmethylene)-1,1-diethyl-2-methylpyrrolidinium bromide; 1,1-Diethyl-2-methyl-3-(di-2-thienylmethylene)pyrrolidinium bromide; 1-Methyl-1-aza-4-azoniaspiro[4.5]decane bromide; Tiquizium bromide (USAN); USAN 8419; Thiaton; Brometo de tiquizio (Portuguese)
EINECS	Contact for details

Quality Control

Our Tiquizium Bromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided, confirming identity, purity, and impurity profiles as per in-house specifications aligned with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.