Description

3-Bromo-2-Chloro-5-(Trifluoromethyl)Pyridine is a high-value halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine, chlorine, and a trifluoromethyl group on the pyridine ring, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for creating specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing substituents.
• Cross-Coupling Reactions: The bromine and chlorine atoms provide distinct sites for selective metal-catalyzed cross-coupling reactions, such as Suzuki, Stille, and Buchwald-Hartwig amination.
• Ligand and Catalyst Development: Utilized in the design and synthesis of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes and tags used in biochemical and diagnostic research.

Basic Information

Product Name	3-Bromo-2-Chloro-5-(Trifluoromethyl)Pyridine
CAS No.	71701-92-3
Molecular Formula	C6H2BrClF3N
Molecular Weight	260.44 g/mol
Synonyms	2-Chloro-3-bromo-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-3-bromo-2-chloropyridine; 3-Bromo-2-chloro-5-trifluoromethylpyridine; Pyridine, 3-bromo-2-chloro-5-(trifluoromethyl)-; 2-Chloro-3-bromo-5-trifluoromethylpyridine; 71701-92-3; BCTFP
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Chloro-5-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept tightly sealed to prevent exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.