Description

2,3-Dichloro-5-Formylpyridine is a versatile and highly functionalized pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of reactive chlorine and aldehyde groups on the heterocyclic ring, enabling precise molecular construction. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its electron-deficient aromatic system.
• Cross-Coupling Reactions: The chlorine atoms make it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to build complex molecular architectures.
• Custom Synthesis and R&D: A fundamental reagent for contract research organizations (CROs) and academic laboratories exploring new chemical entities and reaction pathways.

Basic Information

Product Name	2,3-Dichloro-5-Formylpyridine
CAS No.	71690-05-6
Molecular Formula	C6H3Cl2NO
Molecular Weight	175.00 g/mol
Synonyms	5-Formyl-2,3-dichloropyridine; 2,3-Dichloropyridine-5-carboxaldehyde; 2,3-Dichloro-5-pyridinecarboxaldehyde; 2,3-Dichloropicolinaldehyde; 2,3-Dichloro-5-pyridylaldehyde; 2,3-Dichloro-5-pyridinealdehyde; 2,3-Dichloro-5-pyridinecarbaldehyde; 2,3-Dichloro-5-pyridincarboxaldehyde
EINECS	Contact for details

Quality Control

Our 2,3-Dichloro-5-Formylpyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.