Description

2-O,3-O,4-O,5-o-Tetrabenzoyl-D-Ribose o-Benzyl Oxime is a sophisticated, high-purity chemical intermediate primarily used in advanced organic synthesis and pharmaceutical research. This compound is valued for its role as a protected ribose derivative, enabling precise control over stereochemistry in the construction of complex nucleoside analogs and other bioactive molecules. It is an essential building block for research and development chemists in the pharmaceutical, biotechnology, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer drug discovery.
• Oligonucleotide Synthesis: Used in the preparation of protected ribonucleosides for solid-phase synthesis of RNA and modified oligonucleotides.
• Glycochemistry Research: Serves as a chiral building block for the synthesis of complex carbohydrates and glycoconjugates.
• Chemical Biology Probes: Employed in the development of labeled or modified nucleosides for mechanistic and diagnostic studies.
• Process Development: Utilized in scaling up synthetic routes for active pharmaceutical ingredients (APIs) requiring ribose-based scaffolds.
• Academic & Contract Research: A critical reagent for methodological development in synthetic organic chemistry laboratories.

Basic Information

Product Name	2-O,3-O,4-O,5-o-Tetrabenzoyl-D-Ribose o-Benzyl Oxime
CAS No.	71641-37-7
Molecular Formula	C46H39NO10
Molecular Weight	765.81 g/mol
Synonyms	D-Ribose, 2,3,4,5-tetrakis-O-(phenylcarbonyl)-, O-(phenylmethyl)oxime; Tetrabenzoyl-D-ribose benzyl oxime; 1,2,3,4-Tetra-O-benzoyl-β-D-ribopyranose benzyl oxime; 2,3,4,5-Tetra-O-benzoyl-D-ribonic acid, benzyl oxime; Benzyl 2,3,4,5-tetra-O-benzoyl-D-ribo-pentodialdo-1,5-pyranoside oxime; 71641-37-7
EINECS	Contact for details

Quality Control

Our 2-O,3-O,4-O,5-o-Tetrabenzoyl-D-Ribose o-Benzyl Oxime is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and chiral analysis to ensure stereochemical integrity. We provide full traceability and detailed Certificates of Analysis (COA) to support your regulatory and R&D requirements. Specifications can be tailored to meet specific project needs, including custom purity grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under inert atmosphere when appropriate to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.