Description

Di-p-Toluoyl-D-Tartaric Acid Monohydrate is a high-purity chiral resolving agent and synthetic intermediate of significant commercial importance. Its primary value lies in its ability to separate enantiomers of pharmaceutical compounds and fine chemicals, a critical process for ensuring product efficacy and safety. This compound is essential for manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise chiral separation and high-purity intermediates for advanced synthesis.

Application

• Chiral Resolution Agent: Widely used for the optical resolution of racemic mixtures, particularly for amines and other basic pharmaceuticals, to isolate the desired enantiomer.
• Pharmaceutical Intermediate: Serves as a key building block in the asymmetric synthesis of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• Catalyst and Ligand Precursor: Employed in the preparation of chiral catalysts and ligands for asymmetric catalysis reactions.
• Analytical Chemistry: Used as a chiral selector or derivatizing agent in chromatographic methods like HPLC for enantiomeric purity analysis.
• Agrochemical Synthesis: Applied in the production of enantiomerically pure agrochemicals, such as certain herbicides and pesticides.
• Fine Chemical Production: Utilized in the synthesis of complex, high-value specialty chemicals where chirality is a defining property.

Basic Information

Product Name	Di-p-Toluoyl-D-Tartaric Acid Monohydrate
CAS No.	71607-32-4
Molecular Formula	C20H20O9 • H2O
Molecular Weight	416.38 g/mol (Anhydrous basis: 398.37)
Synonyms	(2R,3R)-2,3-Bis(4-methylbenzoyloxy)succinic acid monohydrate; D-(-)-Di-p-Toluoyltartaric Acid Monohydrate; D-DTTA Monohydrate; (R,R)-O,O'-Di-p-toluoyltartaric acid hydrate; LUMISEPT D 100; D-(-)-Di-p-Toluoyltartaric Acid Hydrate; (2R,3R)-2,3-Bis[(4-methylphenyl)carbonyloxy]butanedioic acid monohydrate
EINECS	Contact for details

Quality Control

Our Di-p-Toluoyl-D-Tartaric Acid Monohydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity assays, to ensure it meets the stringent requirements for chiral resolution and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	3.5 - 5.5%
Specific Rotation [α]20/D	-120° to -130° (c=1 in acetone)
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.