Description

5-((2S)Pyrrolidin-2-Yl)-3-Chloropyridine is a high-value chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules due to its unique pyrrolidine-pyridine hybrid structure and stereogenic center. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, especially for neurological targets.
• Ligand Precursor: Serves as a starting material for the synthesis of sophisticated ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Employed in the discovery and synthesis of new crop protection agents with specific biological activity.
• Chemical Biology Probe Development: Used to create molecular tools for studying enzyme function and protein-protein interactions.
• Academic & Contract Research: A valuable reagent for synthetic organic chemistry research in academic and industrial R&D laboratories.

Basic Information

Product Name	5-((2S)Pyrrolidin-2-Yl)-3-Chloropyridine
CAS No.	71606-33-2
Molecular Formula	C9H11ClN2
Molecular Weight	182.65 g/mol
Synonyms	(S)-2-(5-Chloropyridin-3-yl)pyrrolidine; 3-Chloro-5-[(2S)-2-pyrrolidinyl]pyridine; 5-[(2S)-Pyrrolidin-2-yl]-3-chloropyridine; 3-Chloro-5-((S)-pyrrolidin-2-yl)pyridine; (S)-3-Chloro-5-(pyrrolidin-2-yl)pyridine; 71606-33-2; (2S)-2-(5-Chloro-3-pyridinyl)pyrrolidine
EINECS	Contact for details

Quality Control

We supply 5-((2S)Pyrrolidin-2-Yl)-3-Chloropyridine to high-purity standards suitable for research and development applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) providing detailed specifications for identity, purity, and chiral purity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.