Description

Clinofibrate is a synthetic organic compound belonging to the class of fibrates, which are known for their lipid-modulating properties. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the synthesis of advanced therapeutic agents targeting metabolic disorders. It is primarily utilized by pharmaceutical manufacturers and R&D laboratories engaged in developing treatments for dyslipidemia and related cardiovascular conditions.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of fibrate-class lipid-regulating drugs.
• Research & Development: Used in preclinical and clinical research to study mechanisms of peroxisome proliferator-activated receptor (PPAR) modulation.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in the multi-step manufacturing process of finished dosage forms.
• Metabolic Disorder Studies: Employed in biochemical research focused on triglyceride and cholesterol metabolism pathways.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Clinofibrate
CAS No.	71603-13-9
Molecular Formula	C18H18Cl2O4
Molecular Weight	369.24 g/mol
Synonyms	2-(4'-(p-Chlorophenoxy)phenoxy)-2-methylpropionic Acid Ethyl Ester; CLY-503; Ethyl 2-[4-(4-chlorophenoxy)phenoxy]-2-methylpropanoate; 2-[4-(4-Chlorophenoxy)phenoxy]-2-methylpropanoic Acid Ethyl Ester; Propanoic acid, 2-[4-(4-chlorophenoxy)phenoxy]-2-methyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our Clinofibrate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant ICH guidelines and can support compliance requirements for cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.