Description

Clinofibrate is a synthetic organic compound belonging to the class of fibrates, which are known for their lipid-modulating properties. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the synthesis of advanced therapeutic agents targeting metabolic disorders. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in cardiovascular and metabolic disease research.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel fibrate-based active pharmaceutical ingredients (APIs) for lipid regulation.
• Research & Development: Used in preclinical and clinical research to study mechanisms of action and efficacy of hypolipidemic agents.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical labs.
• Metabolic Disease Studies: Employed in biochemical assays and in-vitro studies focused on peroxisome proliferator-activated receptor (PPAR) activity.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for complex organic molecules within GMP environments.

Basic Information

Product Name	Clinofibrate
CAS No.	71603-12-8
Molecular Formula	C17H16Cl2O4
Molecular Weight	355.22 g/mol
Synonyms	2-(4'-(2,2-Dichlorocyclopropyl)phenoxy)-2-methylpropanoic Acid Isopropyl Ester; CLY-503; Isopropyl 2-[4-[(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoate; 2-[p-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropionic Acid Isopropyl Ester
EINECS	Contact for details

Quality Control

Our Clinofibrate CAS NO 71603-12-8 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identity confirmation via spectroscopic methods (IR, NMR). We provide full traceability and Certificates of Analysis (COA) that detail all test results against stringent in-house specifications, ensuring reliability for your critical R&D and cGMP manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.