Description

Clinofibrate is a synthetic organic compound belonging to the class of fibrates, which are known for their lipid-modulating properties. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the synthesis of advanced therapeutic agents targeting metabolic disorders. It is primarily utilized by pharmaceutical manufacturers and advanced research institutions engaged in developing treatments for dyslipidemia and related cardiovascular conditions.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of fibrate-class lipid-regulating drugs.
• Research & Development: Used in preclinical and clinical research to study mechanisms of peroxisome proliferator-activated receptor (PPAR) modulation.
• Metabolic Disorder Studies: Employed in the development of novel therapeutic agents for hypertriglyceridemia and mixed dyslipidemia.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Chemical Synthesis: Intermediate for further chemical derivatization to create new chemical entities with potential pharmacological activity.

Basic Information

Product Name	Clinofibrate
CAS No.	71603-11-7
Molecular Formula	C18H18O5
Molecular Weight	314.33 g/mol
Synonyms	2-(4-(p-Chlorophenoxy)phenoxy)-2-methylpropanoic Acid; 2-Methyl-2-[4-(4-chlorophenoxy)phenoxy]propanoic Acid; CLY-503; Lipoclin; Propanoic acid, 2-methyl-2-[4-(4-chlorophenoxy)phenoxy]-; 2-[4-(4-Chlorophenoxy)phenoxy]-2-methylpropionic Acid
EINECS	Contact for details

Quality Control

Our Clinofibrate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of the pharmaceutical industry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.