Description

3-(Triethylsilyl)-2-Propynal is a specialized organosilicon building block featuring a reactive alkyne and aldehyde functional group. This compound is valued for its role as a versatile synthon in advanced organic synthesis, enabling the introduction of the triethylsilyl-protected propargyl aldehyde moiety. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds requiring alkyne or propargyl aldehyde functionalization.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides where its unique structure contributes to biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and silicon-containing advanced materials.
• Organic Synthesis Building Block: Employed in various name reactions, including Sonogashira coupling and nucleophilic additions to the aldehyde group, for constructing complex organic molecules.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing novel ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tags for bio-conjugation and labeling studies due to its reactive handles.

Basic Information

Product Name	3-(Triethylsilyl)-2-Propynal
CAS No.	71572-60-6
Molecular Formula	C9H16OSi
Molecular Weight	168.31 g/mol
Synonyms	2-Propynal, 3-(triethylsilyl)-; Triethyl(2-oxoethyl)ethynylsilane; 3-(Triethylsilyl)propiolaldehyde; (Triethylsilyl)propiolaldehyde; 3-Triethylsilylpropiolaldehyde; 3-(Triethylsilyl)prop-2-ynal; 3-TES-propiolaldehyde; 3-(Triethylsilyl)-2-propyn-1-al
EINECS	Contact for details

Quality Control

Our 3-(Triethylsilyl)-2-Propynal is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C due to its sensitivity to moisture and oxidation. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.