Description

2-Chloro-4-(Methylthio)-Pyridine is a versatile halogenated heterocyclic building block of significant importance in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern enables precise molecular modifications. It is primarily needed by research and development chemists, process scale-up engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific functional groups into complex molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry for creating molecules with potential therapeutic activity.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where the pyridine core contributes to biological efficacy.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of functionalized polymers and advanced organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A valuable scaffold for custom chemical synthesis services catering to client-specific R&D projects.
• Academic and Industrial Research: Used in exploratory chemistry to study reaction mechanisms and develop new synthetic methodologies.

Basic Information

Product Name	2-Chloro-4-(Methylthio)-Pyridine
CAS No.	71506-83-7
Molecular Formula	C6H6ClNS
Molecular Weight	159.63 g/mol
Synonyms	2-Chloro-4-(methylthio)pyridine; 4-(Methylthio)-2-chloropyridine; 2-Chloro-4-methylthiopyridine; 2-Chloro-4-(methylsulfanyl)pyridine; Pyridine, 2-chloro-4-(methylthio)-; 2-Chloro-4-(methylmercapto)pyridine; 4-Methylsulfanyl-2-chloropyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(Methylthio)-Pyridine is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality systems are designed to meet the stringent requirements of cGMP for pharmaceutical intermediates and other regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.