Description

2-Ethyl-1-Trimethylsilyloxyhexene is a specialized organosilicon compound featuring a silyl-protected enol ether functional group. This structure makes it a valuable intermediate in organic synthesis, particularly for introducing the 2-ethylhexyl moiety or as a protected carbonyl equivalent under mild conditions. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for steroids and other complex molecules requiring selective protection/deprotection strategies.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the 2-ethylhexyl group can influence solubility and bioavailability.
• Polymer & Material Science: Serves as a monomer or co-monomer precursor in the development of specialty silicones and functional polymers with tailored properties.
• Organic Synthesis Reagent: Acts as a nucleophile or electrophile in carbon-carbon bond-forming reactions, such as aldol-type additions and Michael reactions.
• Flavor & Fragrance Industry: Intermediate for the synthesis of specific ester compounds that contribute to complex scent and flavor profiles.
• Cross-Coupling Reactions: Potential substrate in palladium-catalyzed cross-coupling reactions (e.g., Heck, Stille) for creating more complex olefinic structures.

Basic Information

Product Name	2-Ethyl-1-Trimethylsilyloxyhexene
CAS No.	71504-20-6
Molecular Formula	C11H24OSi
Molecular Weight	200.40 g/mol
Synonyms	1-(Trimethylsilyloxy)-2-ethyl-1-hexene; 2-Ethyl-1-[(trimethylsilyl)oxy]-1-hexene; 2-Ethyl-1-(trimethylsiloxy)hex-1-ene; 1-Hexene, 2-ethyl-1-[(trimethylsilyl)oxy]-; O-Trimethylsilyl-2-ethyl-1-hexen-1-ol; TMS enol ether of 2-ethylhexanal
EINECS	Contact for details

Quality Control

Our 2-Ethyl-1-Trimethylsilyloxyhexene is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment. We adhere to cGMP guidelines for production relevant to pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at 2-8°C or as specified on the label. Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 3.0%
Density (at 20°C)	0.82 - 0.86 g/mL
Refractive Index (n20D)	1.420 - 1.430

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.