Description

1,1-Bis(Trimethylsilyl)-3-(m-Fluorophenyl)-2-Thiourea is a specialized organosilicon thiourea derivative, distinguished by its trimethylsilyl protecting groups and a meta-fluorophenyl substituent. This compound is a valuable synthetic intermediate, offering enhanced stability and reactivity control in complex organic transformations. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of fluorinated drug candidates, particularly those targeting CNS disorders and oncology.
• Organosilicon Chemistry: Serves as a versatile reagent for introducing silyl-protected thiourea functionalities into complex molecules.
• Agrochemical Research: Used in the development of novel fluorinated pesticides and herbicides, leveraging the bioactivity of the thiourea moiety.
• Material Science: Precursor for the synthesis of functionalized polymers and ligands for catalysis.
• Chemical Synthesis: Employed in heterocyclic chemistry for the construction of fluorinated thiazoles, pyrimidines, and other nitrogen-containing heterocycles.
• Academic & R&D: A critical tool for methodological studies in fluorine chemistry and protective group strategies.

Basic Information

Product Name	1,1-Bis(Trimethylsilyl)-3-(m-Fluorophenyl)-2-Thiourea
CAS No.	71457-02-8
Molecular Formula	C13H23FN2SSi2
Molecular Weight	314.57 g/mol
Synonyms	N-(3-Fluorophenyl)-N',N'-bis(trimethylsilyl)thiourea; 1,1-Bis(trimethylsilyl)-3-(3-fluorophenyl)thiourea; 3-(3-Fluorophenyl)-1,1-bis(trimethylsilyl)-2-thiourea; m-Fluorophenyl-1,1-bis(trimethylsilyl)thiourea; Bis(trimethylsilyl)-(3-fluorophenyl)thiourea; N-(m-Fluorophenyl)-N',N'-bis(trimethylsilyl)thiourea; 71457-02-8
EINECS	Contact for details

Quality Control

Our 1,1-Bis(Trimethylsilyl)-3-(m-Fluorophenyl)-2-Thiourea is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is supplied with every batch to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.