Description

n-(2-Methoxyphenyl)Dithiocarbamic Acid Trimethylsilyl Ester is a specialized organosilicon reagent featuring a dithiocarbamate functional group. This compound is valued for its role as a key synthetic intermediate and protecting group in advanced organic synthesis, particularly for introducing sulfur-containing moieties. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, especially those containing dithiocarbamate or thiourea derivatives.
• Agrochemical Synthesis: Used in the research and production of pesticides, herbicides, and fungicides where the dithiocarbamate group imparts biological activity.
• Ligand Precursor: Acts as a precursor for the preparation of dithiocarbamate ligands used in coordination chemistry and catalysis.
• Polymer Modification: Employed in the functionalization of polymers to introduce specific chemical handles or alter material properties.
• Research & Development: A valuable tool in academic and industrial R&D for methodological studies in organosilicon and sulfur chemistry.
• Chemical Proteomics: Can be utilized in activity-based protein profiling (ABPP) and other chemoproteomic applications due to its reactive dithiocarbamate group.

Basic Information

Product Name	n-(2-Methoxyphenyl)Dithiocarbamic Acid Trimethylsilyl Ester
CAS No.	71456-97-8
Molecular Formula	C11H17NOS2Si
Molecular Weight	271.48 g/mol
Synonyms	Trimethylsilyl N-(2-Methoxyphenyl)dithiocarbamate; O-Trimethylsilyl S-(2-Methoxyphenyl) Dithiocarbonate; N-(2-Methoxyphenyl)carbamodithioic Acid Trimethylsilyl Ester; (2-Methoxyphenyl)carbamodithioic Acid O-Trimethylsilyl Ester; TMS-Dithiocarbamate Ester; CAS 71456-97-8
EINECS	Contact for details

Quality Control

Our n-(2-Methoxyphenyl)Dithiocarbamic Acid Trimethylsilyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports development from research quantities to commercial scale under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.