Description

2-Isopropoxy-4-Methyl-[1,3,2]Dioxaborinane is a specialized organoboron reagent, a cyclic boronic ester known for its utility in advanced organic synthesis. This compound is valued for its role as a protected boronic acid equivalent, offering enhanced stability and handling characteristics compared to its acyclic counterparts. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for cross-coupling reactions and as a key synthetic building block.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, air-tolerant boron reagent for forming carbon-carbon bonds in the synthesis of complex molecules.
• Pharmaceutical Intermediate Synthesis: Used in the research and production of active pharmaceutical ingredients (APIs), particularly for introducing aryl and heteroaryl groups.
• Agrochemical Development: Employed in creating novel herbicides, fungicides, and insecticides through targeted molecular construction.
• Materials Science & OLED Research: Acts as a precursor for boron-containing polymers and small molecules used in electronic and optoelectronic devices.
• Chemical Library Synthesis: A valuable tool in medicinal chemistry for the parallel synthesis of diverse compound libraries for screening.
• As a Protecting Group: The cyclic dioxaborinane structure can protect boronic acids from decomposition during multi-step synthetic sequences.

Basic Information

Product Name	2-Isopropoxy-4-Methyl-[1,3,2]Dioxaborinane
CAS No.	71349-55-8
Molecular Formula	C8H17BO3
Molecular Weight	172.03 g/mol
Synonyms	4-Methyl-2-(propan-2-yloxy)-1,3,2-dioxaborinane; 2-Isopropoxy-4-methyl-1,3,2-dioxaborinane; Isopropoxy Methyl Dioxaborinane; 2-(1-Methylethoxy)-4-methyl-1,3,2-dioxaborinane; Cyclic isopropyl methylboronate; (Isopropoxymethylboronic acid cyclic ester); PINACOL (ISOPROPOXY)METHYLBORONATE (common misnomer, structurally related).
EINECS	Contact for details

Quality Control

Our production of 2-Isopropoxy-4-Methyl-[1,3,2]Dioxaborinane adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including NMR, GC, and HPLC. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Purity (NMR)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.