Description

(3R,4S,2E)-2-Hexadec-15-Enylidene)-3-Hydroxy-4-Methylbutanolide is a high-purity, stereochemically defined lactone derivative with a specific unsaturated side chain. This compound is valued for its role as a key chiral building block and intermediate in advanced organic synthesis, enabling the production of complex molecules with precise stereochemistry. It is essential for research and development in the pharmaceutical, agrochemical, and specialty chemical industries, where structural specificity is critical for biological activity and material properties.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of anti-inflammatory, antiviral, or other bioactive compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, or plant growth regulators where the specific stereochemistry influences efficacy.
• Fine Chemical Production: Acts as a building block for creating complex fragrances, flavors, or specialty polymers that require a defined lactone structure.
• Material Science Research: Investigated as a monomer or precursor for biodegradable polymers or advanced materials with specific functional properties.
• Academic & R&D Laboratories: Employed in methodological studies, asymmetric synthesis, and catalysis research within university and corporate R&D settings.

Basic Information

Product Name	(3R,4S,2E)-2-Hexadec-15-Enylidene)-3-Hydroxy-4-Methylbutanolide
CAS No.	71325-94-5
Molecular Formula	C21H36O3
Molecular Weight	336.51 g/mol
Synonyms	2-[(3R,4S,2E)-Hexadec-15-enylidene]-3-hydroxy-4-methylbutanolide; (3R,4S,2E)-2-(Hexadec-15-enylidene)-3-hydroxy-4-methylbutanolide; 3-Hydroxy-4-methyl-2-[(1E)-1-pentadecen-1-yl]-4-butanolide; A stereoisomer of Subglutinol A; Lactone derivative of a C16 unsaturated fatty acid; Chiral butenolide intermediate; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our (3R,4S,2E)-2-Hexadec-15-Enylidene)-3-Hydroxy-4-Methylbutanolide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral HPLC, NMR, and GC/MS, to ensure high chemical and stereochemical purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.