Description

Quadazocine is a synthetic opioid antagonist of significant interest in pharmacological research and development. Its primary value lies in its specific receptor binding profile, making it a crucial reference compound and potential lead structure for novel therapeutic agents. This product is essential for pharmaceutical R&D laboratories, analytical testing facilities, and academic institutions focused on neuropharmacology and analgesic studies. The compound, identified as CAS NO 71276-43-2, is supplied to meet the stringent purity requirements of advanced scientific applications.

Application

• Pharmacological Research: Used as a reference standard and tool compound in studies investigating opioid receptor subtypes, mechanisms of action, and signal transduction pathways.
• Drug Discovery & Development: Serves as a key intermediate or lead molecule in the synthesis and screening of new analgesic and addiction treatment candidates.
• Analytical Reference Standard: Employed in high-performance liquid chromatography (HPLC), mass spectrometry (MS), and nuclear magnetic resonance (NMR) for method development, validation, and quality control of related substances.
• Biochemical Assays: Utilized in in vitro binding assays and functional tests to characterize receptor-ligand interactions and assess compound efficacy.
• Academic & Clinical Studies: Supports fundamental neuroscience research and preclinical investigations into pain management and substance dependence.

Basic Information

Product Name	Quadazocine
CAS No.	71276-43-2
Molecular Formula	C₂₈H₃₄N₂O₃
Molecular Weight	446.59 g/mol
Synonyms	Quadazocine; WIN 44,441; 17-(Cyclopropylmethyl)-6,7-didehydro-4,5α-epoxy-3,14-dihydroxy-6,7:2',3'-indolomorphinan; 2'-(Cyclopropylmethyl)-6,7-didehydro-4,5α-epoxy-3-hydroxy-6,7:2',3'-indolomorphinan-14-ol
EINECS	Contact for details

Quality Control

Every batch of Quadazocine is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for research applications. Our products undergo rigorous quality testing, and a detailed Certificate of Analysis (COA) is supplied with each shipment, documenting key parameters such as assay purity and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). For long-term storage, consider desiccation and an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.