Description

1-tert-Butyl 4-Methyl 1,2,3,4-Tetrahydropyridine-1,4-Dicarboxylate is a high-purity, protected dicarboxylate derivative of tetrahydropyridine, serving as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its value lies in enabling the controlled introduction of functionalized piperidine scaffolds, which are core structures in numerous active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of piperidine-based drug candidates, including potential central nervous system (CNS) agents and receptor modulators.
• Organic Synthesis Building Block: Utilized in multi-step syntheses to construct complex molecular architectures, leveraging the reactivity of both the ester and the tetrahydropyridine ring.
• Agrochemical Research: Intermediate in the development of novel herbicides, fungicides, or insecticides that incorporate saturated nitrogen heterocycles.
• Chemical Biology & Proteomics: Can be used to create specialized molecular probes or linkers for studying biological systems.
• Catalyst & Ligand Development: Serves as a precursor for chiral auxiliaries or ligands used in asymmetric catalysis.
• Academic & R&D Laboratories: Fundamental research reagent for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	1-tert-Butyl 4-Methyl 1,2,3,4-Tetrahydropyridine-1,4-Dicarboxylate
CAS No.	71233-30-2
Molecular Formula	C12H19NO4
Molecular Weight	241.28 g/mol
Synonyms	1,2,3,4-Tetrahydropyridine-1,4-dicarboxylic acid, 1-(1,1-dimethylethyl) 4-methyl ester; 1-(tert-Butyl) 4-methyl 1,2,3,4-tetrahydropyridine-1,4-dicarboxylate; 1-Boc-4-methyl 1,2,3,4-tetrahydropyridine-1,4-dicarboxylate; 1,4-Dicarboxylic acid, 1,2,3,4-tetrahydropyridine-, 1-(1,1-dimethylethyl) 4-methyl ester; 1-tert-Butoxycarbonyl-4-methoxycarbonyl-1,2,3,4-tetrahydropyridine; 1-N-Boc-4-COOMe-1,2,3,4-tetrahydropyridine
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 4-Methyl 1,2,3,4-Tetrahydropyridine-1,4-Dicarboxylate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Typical 98-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.