Description

2-Isocyanatothiazole is a versatile and highly reactive heterocyclic building block used in advanced organic synthesis. Its core value lies in its isocyanate functional group attached to a thiazole ring, enabling the efficient construction of complex molecules like ureas, carbamates, and heterocyclic amides. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, particularly those targeting infectious diseases or metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the thiazole moiety imparts specific biological activity.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or chemical resistance properties.
• Material Science Research: Employed in creating functionalized surfaces, coatings, and advanced materials that require specific chemical linkages.
• Chemical Biology & Proteomics: Utilized as a reactive handle for bioconjugation, labeling biomolecules, or developing activity-based probes.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom chemical synthesis services catering to R&D and scale-up projects.

Basic Information

Product Name	2-Isocyanatothiazole
CAS No.	71189-23-6
Molecular Formula	C4H2N2OS
Molecular Weight	126.14 g/mol
Synonyms	2-Thiazolyl isocyanate; Thiazol-2-yl isocyanate; Isocyanic acid, 2-thiazolyl ester; 2-Isocyanatothiazole; 2-Thiazole isocyanate; NSC 406913; 71189-23-6
EINECS	Contact for details

Quality Control

Every batch of 2-Isocyanatothiazole is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthesis. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to meet the high standards required for research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its moisture-sensitive (hygroscopic) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.