Description

1,4-Dihydro-2,6-Dimethyl-4-(5-Trifluoromethyl-2-Furyl)-3,5-Pyridinedicarboxylic Acid Diethyl Ester is a high-purity, synthetic dihydropyridine derivative, recognized for its role as a key pharmaceutical intermediate. This compound is valued for its structural complexity and its utility in the synthesis of advanced active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical sectors engaged in cardiovascular and neurological drug development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of calcium channel blockers and other dihydropyridine-based active pharmaceutical ingredients (APIs).
• Chemical Research & Development: Used as a reference standard and a starting material for novel compound libraries in medicinal chemistry.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules for agrochemical and material science applications.
• Academic Research: Serves as a model compound for studying structure-activity relationships (SAR) and reaction mechanisms in heterocyclic chemistry.

Basic Information

Product Name	1,4-Dihydro-2,6-Dimethyl-4-(5-Trifluoromethyl-2-Furyl)-3,5-Pyridinedicarboxylic Acid Diethyl Ester
CAS No.	71160-09-3
Molecular Formula	C₁₈H₂₀F₃NO₅
Molecular Weight	387.35 g/mol
Synonyms	4-(5-Trifluoromethyl-2-furyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid diethyl ester; 4-(5-Trifluoromethyl-2-furyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl ester; 1,4-Dihydro-2,6-dimethyl-4-(5-trifluoromethyl-2-furyl)-3,5-pyridinedicarboxylic acid diethyl ester; Diethyl 1,4-dihydro-2,6-dimethyl-4-(5-trifluoromethyl-2-furyl)-3,5-pyridinedicarboxylate; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(5-(trifluoromethyl)-2-furanyl)-, diethyl ester; CAS 71160-09-3
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Quality Control

Our 1,4-Dihydro-2,6-Dimethyl-4-(5-Trifluoromethyl-2-Furyl)-3,5-Pyridinedicarboxylic Acid Diethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.