Description

α-Tosyl-(3,4-Dimethoxybenzyl)Isocyanide is a specialized organic building block of significant interest in advanced synthetic chemistry. This compound matters as a versatile isocyanide reagent, enabling the construction of complex heterocyclic and peptidomimetic frameworks through multicomponent reactions. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the efficient synthesis of novel active ingredients and chemical libraries.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of heterocyclic compounds and peptidomimetics for drug discovery programs.
• Agrochemical Research: Used in the development of novel active ingredients and fungicides through multicomponent reaction chemistry.
• Chemical Library Synthesis: Enables the rapid generation of diverse compound libraries via Passerini and Ugi-type multicomponent reactions for high-throughput screening.
• Material Science: Potential building block for the synthesis of functional polymers and ligands for catalysis.
• Academic Research: Employed in methodological studies to develop new isocyanide-based synthetic transformations.

Basic Information

Product Name	α-Tosyl-(3,4-Dimethoxybenzyl)Isocyanide
CAS No.	71146-67-3
Molecular Formula	C17H17NO4S
Molecular Weight	331.39 g/mol
Synonyms	N-[(3,4-Dimethoxyphenyl)methyl]-4-methylbenzenesulfonamide isocyanide; 4-Methyl-N-[(3,4-dimethoxyphenyl)methyl]benzenesulfonamide isocyanide; 3,4-Dimethoxybenzyl tosyl isocyanide; Tosyl(3,4-dimethoxybenzyl)isocyanide; α-Tosyl-3,4-dimethoxybenzyl isocyanide; TOS-DIMB-IC; (3,4-Dimethoxybenzyl)(tosyl)methyl isocyanide
EINECS	Contact for details

Quality Control

Our α-Tosyl-(3,4-Dimethoxybenzyl)Isocyanide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation and light, prolonged exposure to air or light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.