Description

2',3'-Dihydro-7'-Hydroxy-5'-Methoxyspiro[2,5-Cyclohexadiene-1,1'-[1H]Inden]-4-One is a complex spirocyclic organic compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique fused ring structure makes it a valuable building block for the synthesis of novel molecules with potential biological activity. This high-purity compound is primarily sought by research institutions and pharmaceutical development companies engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or anti-inflammatory targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic candidates.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions for clinical trial material production.
• Organic Synthesis Reference Standard: Employed as a high-purity standard for analytical method development and validation in quality control laboratories.
• Academic Research: Utilized in universities and research institutes for studying spirocyclic compound reactivity and developing new synthetic methodologies.
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals, dyes, or advanced materials requiring complex molecular architectures.

Basic Information

Item	Details
Product Name	2',3'-Dihydro-7'-Hydroxy-5'-Methoxyspiro[2,5-Cyclohexadiene-1,1'-[1H]Inden]-4-One
CAS No.	71135-79-0
Molecular Formula	C15H14O3
Molecular Weight	242.27 g/mol
Synonyms	7'-Hydroxy-5'-methoxyspiro[cyclohexa-2,5-diene-1,1'-inden]-4-one; 2',3'-Dihydro-7'-hydroxy-5'-methoxyspiro[cyclohexa-2,5-diene-1,1'-1H-indene]-4-one; Spiro[cyclohexa-2,5-diene-1,1'-inden]-4-one, 2',3'-dihydro-7'-hydroxy-5'-methoxy-; 71135-79-0; 7-Hydroxy-5-methoxyspiro[cyclohexa-2,5-diene-1,1'-inden]-4-one; 2,3-Dihydro-7-hydroxy-5-methoxyspiro[cyclohexa-2,5-diene-1,1-inden]-4-one
EINECS	Contact for details

Quality Control

Our 2',3'-Dihydro-7'-Hydroxy-5'-Methoxyspiro[2,5-Cyclohexadiene-1,1'-[1H]Inden]-4-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development protocols. Specifications can be aligned with ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.