Description

4-(1-Oxo-2,2,6,6-Tetramethylpiperidyl)-3-Isocyano-n-Propyl Ether is a specialized organic compound featuring a reactive isocyano group tethered to a hindered piperidinyl ether structure. This unique molecular architecture makes it a valuable intermediate for synthesizing advanced materials and fine chemicals where controlled reactivity and steric hindrance are critical. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and polymer industries for applications in catalyst development, ligand synthesis, and the creation of novel functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds requiring sterically hindered amine or nitroxide radical functionalities.
• Polymer Modification & Stabilization: Used to introduce functional isocyanate or amine groups into polymer backbones for cross-linking or to create HALS (Hindered Amine Light Stabilizer) precursors for UV-resistant coatings and plastics.
• Agrochemical Synthesis: Acts as an intermediate in the development of advanced herbicides, fungicides, and plant growth regulators that benefit from its stable, hindered nitroxide moiety.
• Catalyst & Ligand Development: The isocyano group and sterically crowded piperidine ring make it a valuable precursor for designing novel organometallic catalysts and chiral ligands used in asymmetric synthesis.
• Advanced Material Research: Employed in the development of functionalized surfaces, smart polymers, and organic electronic materials where precise molecular architecture is required.
• Nitroxide-Mediated Polymerization (NMP): Functions as a potential controlling agent or alkoxyamine precursor in controlled radical polymerization processes to create polymers with narrow molecular weight distributions.

Basic Information

Product Name	4-(1-Oxo-2,2,6,6-Tetramethylpiperidyl)-3-Isocyano-n-Propyl Ether
CAS No.	71133-03-4
Molecular Formula	C15H26N2O2
Molecular Weight	266.38 g/mol
Synonyms	3-Isocyanopropyl 4-oxo-2,2,6,6-tetramethylpiperidine-1-carboxylate; 1-Oxo-2,2,6,6-tetramethyl-4-piperidinyl 3-isocyanopropanoate; 4-Oxo-TEMPO-3-isocyanopropyl ether; TEMPO-derived isocyanate ether; 4-(3-Isocyanopropoxy)-2,2,6,6-tetramethylpiperidin-1-oxyl; Hindered amine isocyanate intermediate; 71133-03-4
EINECS	Contact for details

Quality Control

Our production of 4-(1-Oxo-2,2,6,6-Tetramethylpiperidyl)-3-Isocyano-n-Propyl Ether adheres to stringent in-process controls and final batch testing to ensure consistent purity and performance. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy for comprehensive characterization. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles to meet your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong acids, bases, and oxidizing agents. Due to the presence of the reactive isocyano group, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.