Description

10-Acetyloxy-6,7-Dihydropyrido[1,2-A]Azepine-6,7,8,9-Tetracarboxylic Acid Tetramethyl Ester is a high-purity, multi-functional heterocyclic building block and advanced pharmaceutical intermediate. This compound is valued for its complex molecular architecture, which serves as a critical scaffold in the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new therapeutic agents and high-value chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Organic Synthesis Building Block: Used in constructing complex polycyclic frameworks for novel materials and chemical libraries.
• Agrochemical Research: Serves as a starting material for developing new active ingredients with potential herbicidal or pesticidal properties.
• Academic & R&D: Employed in medicinal chemistry research for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Fine Chemical Production: Integral in the manufacture of specialty chemicals requiring sophisticated heterocyclic cores.
• Contract Manufacturing (CDMO): Supplied to contract development and manufacturing organizations for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	10-Acetyloxy-6,7-Dihydropyrido[1,2-A]Azepine-6,7,8,9-Tetracarboxylic Acid Tetramethyl Ester
CAS No.	71127-21-4
Molecular Formula	C20H21NO10
Molecular Weight	435.38 g/mol
Synonyms	10-Acetoxy-6,7-dihydropyrido[1,2-a]azepine-6,7,8,9-tetracarboxylic acid tetramethyl ester; Tetramethyl 10-acetyloxy-6,7-dihydro-5H-pyrido[1,2-a]azepine-6,7,8,9-tetracarboxylate; 10-Acetyloxy-6,7-dihydro-5H-pyrido[1,2-a]azepine-6,7,8,9-tetracarboxylic acid tetramethyl ester; 5H-Pyrido[1,2-a]azepine-6,7,8,9-tetracarboxylic acid, 10-(acetyloxy)-6,7-dihydro-, tetramethyl ester; CAS 71127-21-4
EINECS	Contact for details

Quality Control

Our 10-Acetyloxy-6,7-Dihydropyrido[1,2-A]Azepine-6,7,8,9-Tetracarboxylic Acid Tetramethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring high standards, including cGMP manufacturing for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be sensitive to moisture and prolonged exposure to elevated temperatures. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.