Description

2-((3-Chloroethyl)-3-Nitrosoureido)Glucopyranose CAS NO 70866-07-8 is a specialized carbohydrate derivative, notable for its unique chemical structure combining a glucopyranose sugar core with a chloroethyl nitrosourea moiety. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential as a targeted prodrug or a key synthetic intermediate. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel chemotherapeutic agents and targeted drug delivery systems.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel anticancer prodrugs and targeted therapies.
• Bioconjugation Research: Used in studies for attaching cytotoxic agents to sugars, antibodies, or other targeting molecules for site-specific drug delivery.
• Glycobiology Studies: Acts as a tool compound for investigating carbohydrate-based drug metabolism and receptor interactions.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the efficacy and reduce the toxicity of nitrosourea-based compounds.
• Preclinical Development: Utilized in the formulation and testing stages of new chemical entities (NCEs) for oncology applications.

Basic Information

Product Name	2-((3-Chloroethyl)-3-Nitrosoureido)Glucopyranose
CAS No.	70866-07-8
Molecular Formula	C9H16ClN3O7
Molecular Weight	313.69 g/mol
Synonyms	1-(2-Chloroethyl)-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-1-nitrosourea; 2-[(2-Chloroethyl)(nitroso)carbamoyl]amino-2-deoxy-D-glucopyranose; D-Glucose, 2-[[(2-chloroethyl)nitrosoamino]carbonyl]amino-2-deoxy-; Chlorozotocin analog; CCNU-Glucose Derivative
EINECS	Contact for details

Quality Control

Our 2-((3-Chloroethyl)-3-Nitrosoureido)Glucopyranose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.