Description

Proline, 2-Ethenyl-5-Oxo-, Methyl Ester (9Ci) is a specialized proline derivative, a key chiral building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of pharmaceuticals and bioactive molecules, enabling the construction of complex, stereochemically defined structures. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of protease inhibitors, peptidomimetics, and other drug candidates targeting neurological and metabolic diseases.
• Agrochemical Research: Used in the development of novel herbicides and fungicides with specific modes of action, leveraging its proline-based scaffold.
• Peptide Chemistry: Serves as a modified amino acid building block for the solid-phase or solution-phase synthesis of constrained peptides to enhance stability and bioavailability.
• Catalyst Ligand Precursor: Employed in the preparation of chiral ligands for asymmetric catalysis, facilitating enantioselective transformations in fine chemical manufacturing.
• Biochemical Probe Development: Utilized in academic and industrial research to create molecular probes for studying enzyme mechanisms and protein-protein interactions.
• Flavor & Fragrance Chemistry: Acts as an intermediate in the synthesis of complex aroma compounds and specialty ingredients for high-value applications.

Basic Information

Product Name	Proline, 2-Ethenyl-5-Oxo-, Methyl Ester (9Ci)
CAS No.	70805-06-0
Molecular Formula	C8H11NO3
Molecular Weight	169.18 g/mol
Synonyms	2-Vinyl-5-oxoproline methyl ester; Methyl 2-ethenyl-5-oxo-L-prolinate; 5-Oxo-2-vinylproline methyl ester; L-Proline, 2-ethenyl-5-oxo-, methyl ester; (S)-2-Vinyl-5-oxopyrrolidine-2-carboxylic acid methyl ester; 2-Vinyl-5-oxo-L-proline methyl ester; Methyl (S)-2-vinyl-5-oxopyrrolidine-2-carboxylate
EINECS	Contact for details

Quality Control

Our Proline, 2-Ethenyl-5-Oxo-, Methyl Ester (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), and specific impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.