Description

2,2,2-Trichloroethyl 1H-Imidazole-1-Carboxylate is a specialized chemical building block primarily used as a reagent in organic synthesis. Its value lies in its role as a versatile protecting group and activating agent, particularly for carboxylic acids and other functional groups in complex molecule construction. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity intermediates for advanced synthetic routes.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing protecting groups.
• Peptide Synthesis: Used as a coupling agent or for the protection of carboxylic acid moieties during solid-phase and solution-phase peptide synthesis.
• Agrochemical Research: Serves as a building block in the development of novel herbicides, fungicides, and insecticides.
• Fine Chemical Production: Employed in the multi-step synthesis of complex organic molecules, dyes, and specialty polymers.
• Bioconjugation Chemistry: Useful for modifying biomolecules and creating stable conjugates for diagnostic or therapeutic applications.
• Academic & Industrial R&D: A valuable tool for methodological development and exploring new synthetic pathways in laboratory settings.

Basic Information

Product Name	2,2,2-Trichloroethyl 1H-Imidazole-1-Carboxylate
CAS No.	70737-50-7
Molecular Formula	C6H5Cl3N2O2
Molecular Weight	243.47 g/mol
Synonyms	1H-Imidazole-1-carboxylic acid 2,2,2-trichloroethyl ester; 2,2,2-Trichloroethyl imidazole-1-carboxylate; Troc-Imidazole; Trichloroethyl imidazolylformate; Imidazole-1-carboxylic acid trichloroethyl ester; (2,2,2-Trichloroethoxy)carbonyl imidazole; Troc-Im
EINECS	Contact for details

Quality Control

Our 2,2,2-Trichloroethyl 1H-Imidazole-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.