Description

1-Boc-1,2,3,6-Tetrahydropyridine-4-Carboxylic Acid is a high-purity, protected amino acid derivative that serves as a critical building block in advanced organic synthesis. Its primary value lies in providing a versatile and reactive scaffold for constructing complex nitrogen-containing heterocycles and pharmaceutical intermediates. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries, where it is used to develop new active ingredients and novel molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and psychiatric disorders.
• Peptidomimetic Chemistry: Used to incorporate constrained, heterocyclic amino acid analogs into peptide backbones to enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Research: Employed in the discovery and development of new herbicides and insecticides with novel modes of action.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.
• Custom Synthesis Building Block: Utilized by fine chemical manufacturers for the contract synthesis of bespoke molecules for client projects.

Basic Information

Product Name	1-Boc-1,2,3,6-Tetrahydropyridine-4-Carboxylic Acid
CAS No.	70684-84-3
Molecular Formula	C11H17NO4
Molecular Weight	227.26 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-1,2,3,6-tetrahydropyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 1,2,3,6-tetrahydro-1-[(1,1-dimethylethoxy)carbonyl]-; 1-Boc-4-carboxy-1,2,3,6-tetrahydropyridine; Boc-1,2,3,6-THP-4-COOH; tert-Butyl 4-carboxy-3,6-dihydro-2H-pyridine-1-carboxylate; 1-Boc-1,2,3,6-tetrahydro-4-pyridinecarboxylic acid; 1-N-Boc-1,2,3,6-tetrahydropyridine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Boc-1,2,3,6-Tetrahydropyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.