Description

2-Chloropyridine-3-Sulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its bifunctional reactivity, where both the sulfonyl chloride and chloropyridine moieties can be selectively modified to construct complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for the synthesis of sulfonamide-based active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor for the synthesis of novel sulfonamide drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with sulfonamide backbones for enhanced efficacy.
• Material Science: Building block for functional polymers and dyes, where the sulfonyl chloride group facilitates covalent attachment to other components.
• Chemical Research: A valuable reagent in medicinal chemistry for library synthesis and structure-activity relationship (SAR) studies.
• Ligand & Catalyst Development: Used to synthesize specialized pyridine-containing ligands for metal catalysis.

Basic Information

Product Name	2-Chloropyridine-3-Sulfonyl Chloride
CAS No.	70682-09-6
Molecular Formula	C5H3Cl2NO2S
Molecular Weight	212.05 g/mol
Synonyms	3-Chlorosulfonyl-2-chloropyridine; 2-Chloro-3-pyridinesulfonyl chloride; 2-Chloropyridine-3-sulphonyl chloride; 2-Chloro-3-pyridylsulfonyl chloride; 2-Chloro-3-sulfonylchloridopyridine; 70682-09-6; 2-Chloro-3-pyridinesulfonic acid chloride
EINECS	Contact for details

Quality Control

Our 2-Chloropyridine-3-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and reactive nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to maintain stability and prevent hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.