Description

D-(+)-Malic Acid Dimethyl Ester is a high-purity chiral ester derivative of malic acid, serving as a critical chiral building block and resolving agent in advanced organic synthesis. Its value lies in providing enantiomeric purity and structural control for complex molecule construction, which is essential for producing optically active intermediates. This compound is primarily needed by the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis, flavor and fragrance development, and polymer research.

Application

• Asymmetric Synthesis: A key chiral synthon for constructing enantiomerically pure pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
• Chiral Resolution Agent: Used to separate racemic mixtures of acids or amines via diastereomeric salt formation.
• Flavor & Fragrance Industry: Acts as a precursor for synthesizing specific, high-value flavor esters and aroma chemicals.
• Agrochemical Synthesis: Employed in the production of chiral pesticides and herbicides where specific stereochemistry is required for bioactivity.
• Polymer Chemistry: Serves as a monomer or co-monomer for creating specialized polyesters with tailored properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and catalysis studies.

Basic Information

Product Name	D-(+)-Malic Acid Dimethyl Ester
CAS No.	70681-41-3
Molecular Formula	C6H10O5
Molecular Weight	162.14 g/mol
Synonyms	Dimethyl D-Malate; (R)-(-)-Dimethyl Malate; D-(-)-Dimethyl Malate; (R)-Dimethyl 2-Hydroxysuccinate; Dimethyl (R)-(-)-Malate; Methyl (R)-(-)-Malate; (2R)-2-Hydroxybutanedioic Acid Dimethyl Ester; D-Malic Acid Dimethyl Ester
EINECS	Contact for details

Quality Control

Our D-(+)-Malic Acid Dimethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay and impurity profiling, to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) detailing specific results for identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]20/D	-25° to -30° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.