Description

4,6-Dichloro-Nicotinamide is a halogenated pyridine derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce the nicotinamide pharmacophore with specific halogen substitution patterns.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the dichloro-nicotinamide scaffold provides specific bioactivity.
• Chemical Research & Development: Serves as a versatile precursor for further functionalization (e.g., cross-coupling reactions, nucleophilic substitutions) in academic and industrial labs.
• Ligand and Complex Formation: Potential use in creating specialized ligands for catalytic systems or metal-organic frameworks (MOFs).
• Material Science Precursor: Can be utilized in the synthesis of organic electronic materials or functional polymers.

Basic Information

Product Name	4,6-Dichloro-Nicotinamide
CAS No.	70593-57-6
Molecular Formula	C6H4Cl2N2O
Molecular Weight	191.01 g/mol
Synonyms	4,6-Dichloropyridine-3-carboxamide; 3-Carbamoyl-4,6-dichloropyridine; Nicotinamide, 4,6-dichloro-; 4,6-Dichloro-3-pyridinecarboxamide; 4,6-Dichloronicotinamide
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-Nicotinamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.