Description

L-Aspartic Acid Di-tert-Butyl Ester Dibenzenesulfimide Salt is a high-purity, protected amino acid derivative primarily used as a critical building block in advanced organic synthesis. This compound is essential for the preparation of peptides and peptidomimetics, offering enhanced solubility and protection of the reactive carboxyl and amino groups during complex coupling reactions. It is a key intermediate for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors developing novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediate: A crucial protected precursor in the solid-phase and solution-phase synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used to incorporate aspartic acid residues into peptide chains while preventing unwanted side reactions, essential for research and production.
• Bioconjugation & Labeling: Serves as a modified amino acid scaffold for creating labeled peptides or protein conjugates for diagnostic and research applications.
• Medicinal Chemistry Research: Employed in the design and synthesis of novel drug candidates, enzyme inhibitors, and receptor ligands.
• Fine Chemical Synthesis: Acts as a chiral building block for the asymmetric synthesis of complex organic molecules with high stereochemical purity.

Basic Information

Product Name	L-Aspartic Acid Di-tert-Butyl Ester Dibenzenesulfimide Salt
CAS No.	70534-48-4
Molecular Formula	C26H36N2O6S
Molecular Weight	504.64 g/mol
Synonyms	H-Asp(OtBu)2-OSu; L-Aspartic acid β-tert-butyl ester α-tert-butyl ester N-hydroxysuccinimide ester; N-(tert-Butoxycarbonyl)-L-aspartic acid α-tert-butyl ester; Boc-Asp(OtBu)-OH N-hydroxysuccinimide ester; Aspartic acid, N-(1,1-dimethylethoxy)carbonyl-, 1-(1,1-dimethylethyl) ester, 2,5-dioxo-1-pyrrolidinyl ester; (2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]butanedioic acid 1-tert-butyl ester 4-(2,5-dioxopyrrolidin-1-yl) ester; NSC 334904; Protected L-Aspartic Acid NHS Ester
EINECS	Contact for details

Quality Control

Our L-Aspartic Acid Di-tert-Butyl Ester Dibenzenesulfimide Salt is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.