Description

Prodan CAS NO 70504-01-7 is a highly sensitive and versatile fluorescent molecular probe, specifically 6-propionyl-2-(dimethylamino)naphthalene. Its value lies in its exceptional solvatochromic properties, where its emission spectrum shifts dramatically in response to changes in the polarity and viscosity of its local microenvironment. This makes it an indispensable tool for researchers and formulators in the life sciences and advanced materials sectors who need to study membrane dynamics, protein folding, polymer microenvironments, and micelle formation with high precision.

Application

• Membrane Biophysics Research: As a polarity-sensitive probe for studying lipid bilayer properties, phase transitions, and the organization of cellular membranes.
• Protein Conformation Analysis: To monitor protein folding, unfolding, and ligand-binding events by labeling specific sites and detecting microenvironmental changes.
• Polymer Science & Material Characterization: For investigating the micropolarity, free volume, and glass transition temperatures within polymers, gels, and composite materials.
• Colloid & Surface Chemistry: Used in the study of micelles, reverse micelles, vesicles, and other self-assembled systems to determine critical micelle concentration (CMC) and aggregation behavior.
• Fluorescence Spectroscopy & Imaging: A key reagent in advanced fluorescence techniques, including fluorescence lifetime imaging microscopy (FLIM) and ratiometric sensing applications.
• Drug Delivery System Research: To probe the encapsulation efficiency and release kinetics of active pharmaceutical ingredients (APIs) from nanocarriers like liposomes and nanoparticles.

Basic Information

Product Name	Prodan
CAS No.	70504-01-7
Molecular Formula	C₁₅H₁₇NO₂
Molecular Weight	243.30 g/mol
Synonyms	6-Propionyl-2-(dimethylamino)naphthalene; 2-Dimethylamino-6-propionylnaphthalene; PRODAN; 6-Propionyl-N,N-dimethyl-2-naphthylamine; N,N-Dimethyl-6-propionyl-2-naphthylamine; Environment-Sensitive Fluorescent Probe PRODAN; Solvatochromic Fluorescent Dye PRODAN
EINECS	Contact for details

Quality Control

Our Prodan is manufactured under strict quality management systems to ensure batch-to-batch consistency and high performance for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods to confirm its solvatochromic properties. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and key performance characteristics.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Approx. 120 - 124 °C
Fluorescence Properties	Exhibits characteristic solvatochromic shift
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.