Description

2-Bromo-5-Formylnicotinonitrile is a versatile and high-value brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique bifunctional structure, featuring both a formyl group and a nitrile, enables precise molecular construction for complex heterocyclic systems. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides by constructing complex pyridine-based active molecules.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Acts as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Stille) and as a substrate for nucleophilic aromatic substitution, enabling diverse molecular diversification.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and for creating bespoke compound libraries for high-throughput screening.

Basic Information

Product Name	2-Bromo-5-Formylnicotinonitrile
CAS No.	70416-48-7
Molecular Formula	C7H3BrN2O
Molecular Weight	211.02 g/mol
Synonyms	5-Formyl-2-bromonicotinonitrile; 2-Bromo-5-formyl-3-cyanopyridine; 3-Cyano-2-bromo-5-pyridinecarboxaldehyde; 2-Bromo-5-pyridinecarboxaldehyde-3-carbonitrile; Nicotinonitrile, 2-bromo-5-formyl-; 70416-48-7; 2-Bromo-5-formyl-3-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Formylnicotinonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for pharmaceutical intermediates, ensuring traceability and documentation for regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for prolonged stability, especially after opening.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.