Description

Tetramethylrhodamine is a high-purity, fluorescent dye belonging to the rhodamine family, widely recognized for its excellent photostability and bright orange-red emission. Its core value lies in providing reliable, intense fluorescence for sensitive detection and imaging applications, making it a critical component in advanced research and diagnostics. This product is essential for professionals in biotechnology, pharmaceutical development, and analytical chemistry who require consistent performance for labeling, tracing, and assay development. We supply Tetramethylrhodamine CAS NO 70281-37-7 to the global market with a commitment to stringent quality control and supply chain reliability.

Application

• Fluorescent Labeling and Staining: Used as a covalent label for antibodies, proteins, peptides, and nucleic acids in fluorescence microscopy (FISH), flow cytometry, and immunohistochemistry.
• Biomolecular Tracing: Acts as a vital tracer in cell biology for tracking intracellular dynamics, organelle labeling, and monitoring endocytic pathways.
• Diagnostic Assay Development: Serves as a key fluorescent reporter in the development of ELISA, lateral flow assays, and other in vitro diagnostic (IVD) kits.
• Materials Science Research: Employed in the development of fluorescent sensors, probes, and functional materials due to its tunable photophysical properties.
• Academic and Industrial R&D: A fundamental tool in life science research for studying protein-protein interactions, receptor binding, and enzymatic activity.

Basic Information

Product Name	Tetramethylrhodamine
CAS No.	70281-37-7
Molecular Formula	C25H30N2O3
Molecular Weight	406.52 g/mol
Synonyms	TAMRA; 5(6)-Tetramethylrhodamine; Tetramethylrhodamine-5(6)-isomer; Rhodamine 101 methyl ester; 9-(2-Carboxyphenyl)-3,6-bis(dimethylamino)xanthylium chloride; C.I. 45175; Basic Violet 11; [9-(2-Carboxyphenyl)-6-(dimethylamino)-3H-xanthen-3-ylidene]-dimethylammonium chloride
EINECS	Contact for details

Quality Control

Our Tetramethylrhodamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectrophotometry for absorbance/fluorescence verification, and identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring the product meets the high standards required for research and diagnostic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term stability, consider storing under inert atmosphere.

Specification

Item	Specification
Appearance	Dark red to purple powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Absorption Maximum (λmax)	540 - 560 nm
Emission Maximum	565 - 585 nm
Loss on Drying	≤ 2.0 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.