Description

(1R,5S)-Spiro[Bicyclo[3.2.1]Octane-8,2'-[1,3]Dioxolan]-3-One is a high-purity, stereochemically defined spirocyclic compound featuring a fused bicyclic and dioxolane structure. This compound is valued as a versatile chiral building block and advanced pharmaceutical intermediate for the synthesis of complex organic molecules. It is primarily needed by pharmaceutical R&D laboratories, agrochemical manufacturers, and specialty chemical producers developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of central nervous system (CNS) drugs, antiviral agents, and other therapeutic small molecules.
• Agrochemical Synthesis: Building block for creating novel, stereospecific pesticides and herbicides with enhanced efficacy.
• Asymmetric Catalysis: Potential ligand precursor or chiral auxiliary in catalytic processes requiring rigid, defined stereochemistry.
• Material Science Research: Precursor for specialty polymers or liquid crystals where the spirocyclic core imparts specific physical properties.
• Academic & Industrial R&D: Used in methodological studies and process chemistry for constructing complex polycyclic frameworks.
• Flavor & Fragrance Industry: Intermediate for synthesizing musky or woody odorants with high stability.

Basic Information

Product Name	(1R,5S)-Spiro[Bicyclo[3.2.1]Octane-8,2'-[1,3]Dioxolan]-3-One
CAS No.	70260-47-8
Molecular Formula	C10H14O3
Molecular Weight	182.22 g/mol
Synonyms	(1R,5S)-Spiro[bicyclo[3.2.1]octane-8,2'-[1,3]dioxolan]-3-one; (1R,5S)-3-Oxaspiro[bicyclo[3.2.1]octane-8,2'-[1,3]dioxolane]; 3-Oxaspiro[bicyclo[3.2.1]octane-8,2'-[1,3]dioxolane], (1R,5S)-; (1R,5S)-8,9-Dioxatricyclo[5.2.1.01,5]decan-4-one; Spirocyclic dioxolane ketone; Bicyclo[3.2.1]octane dioxolane derivative
EINECS	Contact for details

Quality Control

Our (1R,5S)-Spiro[Bicyclo[3.2.1]Octane-8,2'-[1,3]Dioxolan]-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be sensitive to prolonged exposure to moisture and should be handled under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.