Description

2-Chloro-5-(Chloromethyl)Pyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a chloro and a reactive chloromethyl group on the pyridine ring, makes it a valuable intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and other therapeutic areas.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides, herbicides, and fungicides, where the pyridine core is a common bioactive motif.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of functional polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The chloromethyl group provides a handle for further functionalization via Suzuki, Heck, or other palladium-catalyzed cross-coupling reactions.
• Custom Synthesis and R&D: A fundamental reagent for contract research organizations (CROs) and academic laboratories exploring new chemical spaces and reaction pathways.

Basic Information

Product Name	2-Chloro-5-(Chloromethyl)Pyridine
CAS No.	70258-18-3
Molecular Formula	C6H5Cl2N
Molecular Weight	162.02 g/mol
Synonyms	5-(Chloromethyl)-2-chloropyridine; 2-Chloro-5-chloromethylpyridine; 2-Chloro-5-(chloromethyl)pyridine; (2-Chloro-5-pyridinyl)methyl chloride; 2-Chloro-5-pyridinemethanol chloride; 70258-18-3; 5-(Chloromethyl)-2-chloro-pyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(Chloromethyl)Pyridine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor quality systems to meet specific customer and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.