Description

4-(Chloromethyl)Pyridine 1-Oxide is a versatile and reactive heterocyclic building block, primarily valued for its dual functionality as an N-oxide and a chloromethyl group. This compound is crucial for facilitating complex molecular transformations and constructing advanced chemical architectures in pharmaceutical and agrochemical research. It is essential for chemists and R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries who require a high-purity intermediate for synthesizing active pharmaceutical ingredients (APIs), ligands, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug molecules, particularly those containing pyridine or pyridine N-oxide pharmacophores.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the chloromethyl group enables further derivatization.
• Ligand Precursor: Serves as a starting material for the preparation of N-oxide-based ligands used in catalysis and metal coordination chemistry.
• Chemical Research & Development: Employed in organic synthesis for introducing the chloromethylpyridine moiety into larger molecular frameworks.
• Material Science: Potential use in the synthesis of functional polymers and advanced organic materials.

Basic Information

Product Name	4-(Chloromethyl)Pyridine 1-Oxide
CAS No.	70258-17-2
Molecular Formula	C6H6ClNO
Molecular Weight	143.57 g/mol
Synonyms	4-(Chloromethyl)pyridine N-Oxide; 4-Picolyl Chloride N-Oxide; 1-Oxido-4-(chloromethyl)pyridin-1-ium; Pyridine, 4-(chloromethyl)-, 1-oxide; 4-Chloromethylpyridine N-Oxide; 4-Picolylchloride Oxide; 4-(Chloromethyl)pyridine 1-Oxide Hydrochloride (salt form)
EINECS	Contact for details

Quality Control

Our 4-(Chloromethyl)Pyridine 1-Oxide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.