Description

Ethyl 3-(2-Fluorophenyl)-3-Hydroxypropanoate is a high-value fluorinated organic intermediate characterized by its chiral hydroxy ester functionality. This compound matters for its role as a critical building block in the synthesis of complex pharmaceutical molecules and advanced agrochemicals, where the fluorine atom and β-hydroxy ester moiety are key to modulating biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory drugs.
• Agrochemical Synthesis: Building block for developing novel herbicides and fungicides, where the fluorine atom enhances lipophilicity and target binding.
• Chiral Auxiliary & Resolving Agent: Utilized in asymmetric synthesis due to the presence of a stereogenic center for the production of enantiomerically pure compounds.
• Fine Chemical Research: Serves as a versatile starting material in academic and industrial research for exploring new fluorinated compound libraries.
• Liquid Crystal & Electronic Material Precursor: Potential intermediate in the synthesis of fluorinated components for advanced display and electronic applications.

Basic Information

Product Name	Ethyl 3-(2-Fluorophenyl)-3-Hydroxypropanoate
CAS No.	70200-11-2
Molecular Formula	C11H13FO3
Molecular Weight	212.22 g/mol
Synonyms	Ethyl 3-Hydroxy-3-(2-fluorophenyl)propanoate; 3-(2-Fluorophenyl)-3-hydroxypropionic Acid Ethyl Ester; β-Hydroxy-β-(2-fluorophenyl)propionic Acid Ethyl Ester; 2-Fluorophenyl-3-hydroxypropanoic Acid Ethyl Ester; Ethyl 3-Hydroxy-3-(o-fluorophenyl)propionate; NSC 405124; FPHPE
EINECS	Contact for details

Quality Control

Our Ethyl 3-(2-Fluorophenyl)-3-Hydroxypropanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the stringent requirements for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (Typical for specific grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.