Description

2-Chloro-4,6-Dihydroxypyridine-3-Carboxaylic Acid Ethyl Ester is a versatile pyridine derivative ester, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its functionalized structure, which provides reactive sites for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds and fine-tune material properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, dyes, and photoactive compounds due to its conjugated pyridine system.
• Chemical Research & Development: A valuable reagent for method development and exploring new synthetic pathways in academic and industrial R&D laboratories.
• Fine Chemical Production: Integrated into multi-step syntheses for producing high-value, low-volume specialty chemicals with specific functional properties.

Basic Information

Item	Details
Product Name	2-Chloro-4,6-Dihydroxypyridine-3-Carboxaylic Acid Ethyl Ester
CAS No.	70180-38-0
Molecular Formula	C8H8ClNO4
Molecular Weight	217.61 g/mol
Synonyms	Ethyl 2-Chloro-4,6-dihydroxynicotinate; 2-Chloro-4,6-dihydroxynicotinic Acid Ethyl Ester; 3-Carbethoxy-2-chloro-4,6-dihydroxypyridine; 2-Chloro-4,6-dihydroxy-3-pyridinecarboxylic Acid Ethyl Ester; Ethyl 2-Chloro-4,6-dihydroxypyridine-3-carboxylate; 70180-38-0; 2-Chloro-4,6-dihydroxypyridine-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-4,6-Dihydroxypyridine-3-Carboxaylic Acid Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. The material undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) documenting all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.