Description

6-Cyanonicotinic Acid is a versatile and high-purity organic building block, specifically a pyridine derivative functionalized with both a carboxylic acid and a nitrile group. This bifunctional structure makes it a critical intermediate for synthesizing complex molecules in advanced research and industrial applications. It is primarily utilized by pharmaceutical, agrochemical, and specialty chemical manufacturers for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of modern pesticides and herbicides, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the design and synthesis of functional organic materials, such as metal-organic frameworks (MOFs) and conductive polymers.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tags for studying biological processes.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up production under cGMP for clinical trial materials.

Basic Information

Product Name	6-Cyanonicotinic Acid
CAS No.	70165-31-0
Molecular Formula	C7H4N2O2
Molecular Weight	148.12 g/mol
Synonyms	6-Cyanopyridine-3-carboxylic Acid; 3-Cyano-5-pyridinecarboxylic Acid; 5-Cyanonicotinic Acid; Nicotinic acid, 6-cyano-; 6-Cyano-3-pyridinecarboxylic Acid; 3-Carboxy-5-cyanopyridine; 6-CN-NA
EINECS	Contact for details

Quality Control

Our 6-Cyanonicotinic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and heavy metals. Certificates of Analysis (COA) with full traceability are provided for each shipment, ensuring compliance with research and cGMP-grade requirements for advanced synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.