Description

2-(4-Bromo-Benzyl)-Malonic Acid Diethyl Ester is a versatile brominated malonic ester derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the reactive malonate moiety and the bromobenzyl group, which provide handles for further functionalization and carbon-carbon bond formation. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing complex molecular architectures, active pharmaceutical ingredients (APIs), and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers and advanced organic materials.
• Organic Synthesis: Employed in Knoevenagel condensations, alkylations, and other C-C bond-forming reactions to create complex esters and carboxylic acids.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry in exploring new synthetic pathways.
• Fine Chemical Production: Integral to the manufacture of high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Product Name	2-(4-Bromo-Benzyl)-Malonic Acid Diethyl Ester
CAS No.	70146-78-0
Molecular Formula	C₁₄H₁₇BrO₄
Molecular Weight	329.19 g/mol
Synonyms	Diethyl 2-[(4-Bromophenyl)methyl]propanedioate; Diethyl (4-Bromobenzyl)malonate; Propanedioic acid, 2-[(4-bromophenyl)methyl]-, 1,3-diethyl ester; 2-(4-Bromobenzyl)malonic Acid Diethyl Ester; 1,3-Diethyl 2-(4-bromobenzyl)propanedioate; (4-Bromobenzyl)malonic Acid Diethyl Ester; Diethyl (4-Bromobenzyl)propanedioate
EINECS	Contact for details

Quality Control

Our 2-(4-Bromo-Benzyl)-Malonic Acid Diethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to quality assurance ensures the material meets the high standards required for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.